TY  - ADVS
AU  - Copeland,Robert Allen
TI  - Enzymology in drug discovery: part 2 of 2 
T2  - Small molecule drug discovery,
PY  - 2013///
CY  - London
PB  - Henry Stewart Talks
KW  - Drugs
KW  - Design
KW  - Enzyme inhibitors
KW  - Structure-activity relationships
KW  - Therapeutic use
KW  - Enzymes
KW  - Enzymology
KW  - Pharmaceutical chemistry
KW  - Drug Design
KW  - Drug Discovery
KW  - Enzyme Inhibitors
KW  - chemistry
KW  - metabolism
KW  - pharmacology
KW  - therapeutic use
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for; Access restricted to subscribers
UR  - https://hstalks.com/bs/2638/
UR  - https://hstalks.com/bs/p/739/
ER  -