TY - ADVS AU - Lipinski,Christopher A. TI - Rules and filters and their impact on success in chemical biology and drug discovery T2 - Small molecule drug discovery, PY - 2014/// CY - London PB - Henry Stewart Talks KW - Drug development KW - Drugs KW - Design KW - Research KW - Pharmaceutical chemistry KW - Chemistry, Pharmaceutical KW - methods KW - Computational Biology KW - Drug Discovery KW - Drug Evaluation, Preclinical N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Academic targets and the translational gap -- Chemistry & attrition (Reductionism, genomics and high throughput screening) -- Screening diverse compounds (advantages and disadvantages) -- Medicinal chemistry (A pattern recognition discipline) -- Biology and chemistry networks analysis -- Ligand efficiency and selectivity; Access restricted to subscribers UR - https://hstalks.com/bs/2778/ UR - https://hstalks.com/bs/p/739/ ER -