TY  - ADVS
AU  - Hanley,Jonathan
TI  - Postsynaptic scaffold proteins in health and disease
T2  - Synapses, neurotransmitters and receptor channels,
PY  - 2014///
CY  - London
PB  - Henry Stewart Talks
KW  - Brain
KW  - Diseases
KW  - Pathophysiology
KW  - Neuronal plasticity
KW  - Protein-protein interactions
KW  - Synapses
KW  - Physiology
KW  - Synaptic transmission
KW  - Brain Diseases
KW  - physiopathology
KW  - Nerve Tissue Proteins
KW  - metabolism
KW  - Neuronal Plasticity
KW  - physiology
KW  - Synaptic Transmission
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Multi-domain structure of scaffold proteins allows multiple protein-protein interactions -- They localise important signaling proteins close to neurotransmitter receptor complexes -- Scaffold proteins at excitatory synapses underpin synaptic plasticity by regulating AMPA receptor trafficking and dendritic spine morphology -- Mutations in scaffold proteins underlie neuropsychiatric diseases such as autism and schizophrenia -- Other diseases including Alzheimers and stroke also involve mechanisms incorporating postsynaptic scaffold proteins; Access restricted to subscribers
UR  - https://hstalks.com/bs/2777/
UR  - https://hstalks.com/bs/p/798/
ER  -