TY - ADVS AU - Lewis,Patrick A. TI - Deciphering neurodegeneration: models and methods T2 - The genetic basis of neurological disorders, PY - 2014/// CY - London PB - Henry Stewart Talks KW - Nervous system KW - Degeneration KW - Animal models KW - Genetic aspects KW - Diseases KW - Neurophysiology KW - Research KW - Models, Animal KW - Models, Genetic KW - Models, Molecular KW - Nervous System Diseases KW - genetics KW - Neurodegenerative Diseases N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Deciphering Neurodegeneration: Models and Methods -- The challenge of neurodegeneration -- Huge diversity in cell types -- Nature versus nurture -- Reductionism versus systems biology -- Cellular models -- Yeast -- Primary cells -- Cell lines -- Stem cells -- Model organisms -- Caenorhabditis elegans -- Drosophila melanogaster -- Zebrafish -- Danio rerio -- Rodents -- Molecular biology approaches -- Knock out and knock in -- Genomic editing -- RNAi -- Overexpression -- Gene expression -- rtPCR -- Microarrays -- RNAseq -- Protein analysis -- Immunoblot -- ELISA -- Mass spec and proteomics -- Microscopy -- Immunocytochemistry -- Live cell imaging -- Electrophysiology; Access restricted to subscribers UR - https://hstalks.com/bs/2854/ UR - https://hstalks.com/bs/p/908/ ER -