TY - ADVS AU - Schoeberl,Birgit TI - A systems biology approach to oncology drug development: clinical testing of biomarkers for the anti-ErbB3 antibody MM-121 T2 - Systems biology, PY - 2015/// CY - London PB - Henry Stewart Talks KW - Antineoplastic agents KW - Development KW - Computational biology KW - Drug development KW - Pharmaceutical technology KW - Data processing KW - Antibodies, Monoclonal KW - pharmacology KW - Antineoplastic Agents KW - Cell Line, Tumor KW - Drug Design KW - Drug Discovery KW - Genes, erbB KW - Ligands KW - Neoplasms KW - drug therapy KW - Receptor, ErbB-3 KW - antagonists & inhibitors KW - immunology KW - Systems Biology KW - Technology, Pharmaceutical KW - methods N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Oncology drug development -- Network biology -- The HRG family of ligands -- The ErbB pathway -- MM-121 mechanism of action -- Data from in-vitro and iv-vivo experiments using MM-121 -- Timeline of MM-121: 2003-2015; Access restricted to subscribers UR - https://hstalks.com/bs/3104/ UR - https://hstalks.com/bs/p/876/ ER -