TY - ADVS AU - Reardon,David A. TI - Immune checkpoint blockade in CNS tumors T2 - Immunotherapy of cancer, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Antineoplastic agents KW - Brain KW - Cancer KW - Chemotherapy KW - Immunological aspects KW - Treatment KW - Central nervous system KW - Glioblastoma Multiforme KW - Immunotherapy KW - Antineoplastic Agents KW - therapeutic use KW - Brain Neoplasms KW - drug therapy KW - immunology KW - Central Nervous System Neoplasms KW - Glioblastoma KW - therapy KW - Immunologic Factors KW - pharmacology KW - Immunologic Memory KW - Immunosuppressive Agents N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Immunotherapy in oncology -- CNS immunoprivilege -- Glioblastoma (GBM): complexity/redundancy/heterogeneity -- "Established" and "Advanced" GBM models -- Tumor-specific immune response in GBM -- Importance of heterogeneity -- Overcoming challenges for durable GBM benefit -- Neoantigen mutations -- Checkpoint blockade & immunologic memory -- GBM vaccines -- Personalized neoantigen vaccine ("NeoVax") -- Immunotherapy response assessment in neuro-oncology (iRANO) -- Clinical trials in neuro-oncology -- Immunosuppressive mechanisms in GBM -- Combination anti-tumor immunotherapy; Access restricted to subscribers UR - https://hstalks.com/bs/3225/ UR - https://hstalks.com/bs/p/896/ ER -