TY - ADVS AU - Torday,John S. TI - On the utility of a mechanistic approach to physiology: part 2, the evolutionary origin of endothermy T2 - Evolutionary physiology, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Cell interaction KW - Evolution (Biology) KW - Lungs KW - Evolution KW - Molecular evolution KW - Warm-blooded animals KW - Acclimatization KW - Adaptation, Physiological KW - Biological Evolution KW - Body Temperature Regulation KW - genetics KW - Cell Communication KW - Cholesterol KW - Endocrine System KW - Energy Metabolism KW - Evolution, Molecular KW - Gene Duplication KW - Homeostasis KW - Lung KW - physiology KW - Oxygen KW - Parathyroid Hormone-Related Protein KW - Phylogeny KW - Receptors, Adrenergic, beta KW - Receptors, Glucocorticoid KW - Receptors, Parathyroid Hormone N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Evolution of endothermy -- PTHrP, Glucocorticoid and β-Adrenergic Receptor gene duplications -- Hypoxia integrates respiratory and endocrine systems -- Selection pressure for integrated physiology: lung, kidney, heart -- Ontogeny-phylogeny of lung cell evolution -- Swim bladder-lung functional homology -- PTHrP is stretch-regulated -- Chemiosmosis-homeostasis and the origins of life -- Vertical integration of the effect of cholesterol on homeostasis -- Cell-cell interactions and adaptation to oxygen -- Endothermy as exaptation of oxygen adaptation -- Physiologic homology based on cell-cell interactions; Access restricted to subscribers UR - https://hstalks.com/bs/3241/ UR - https://hstalks.com/bs/p/962/ ER -