TY - ADVS AU - Guengerich,F.Peter TI - Cytochrome P450 1 family: the roles of 1A1, 1A2 and 1B1 in drug metabolism T2 - Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Antineoplastic agents KW - Cancer KW - Chemotherapy KW - Cytochrome P-450 KW - Physiological effect KW - Drug development KW - Drugs KW - Metabolism KW - Antineoplastic Agents KW - Cytochrome P-450 Enzyme System KW - genetics KW - metabolism KW - Drug Discovery KW - Drug-Related Side Effects and Adverse Reactions KW - Inactivation, Metabolic KW - Molecular Epidemiology KW - Neoplasms KW - drug therapy KW - Pharmaceutical Preparations KW - Polymorphism, Genetic N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Family 1 P450 -- Substrates -- Regulation -- Polymorphisms -- Levels of activity and cancer -- Adverse drug reactions -- P450 systems and drug development -- Molecular epidemiology in cancer issues; Access restricted to subscribers UR - https://hstalks.com/bs/684/ UR - https://hstalks.com/bs/p/16/ ER -