TY - ADVS AU - Stingl,Julia TI - Clinical importance of pharmacogenetic polymorphisms affecting drug metabolism: Part II. Internal medicine T2 - Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Cytochrome P-450 KW - Drugs KW - Metabolism KW - Pharmacogenetics KW - Cytochrome P-450 Enzyme System KW - Enzymes KW - pharmacokinetics KW - Inactivation, Metabolic KW - Pharmaceutical Preparations KW - metabolism KW - methods KW - Polymorphism, Genetic KW - Risk Assessment N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Genetic variability in pharmacokinetics -- Polymorphic drug-metabolizing enzymes (Cytochrome P450) -- Implementation of pharmacogenetics in drug therapy -- Risks and benefits of being a poor metabolizer -- Limitations of genetics-based dose adjustments -- Future clinical study directions in pharmacogenetics; Access restricted to subscribers UR - https://hstalks.com/bs/698/ UR - https://hstalks.com/bs/p/16/ ER -