TY - ADVS AU - Maiorino,Matilde TI - Selenium and male fertility T2 - Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Fertility, Human KW - Oxidative stress KW - Selenium KW - chemistry KW - Spermatogenesis KW - Spermatozoa KW - Physiology KW - Antioxidants KW - metabolism KW - Cell Survival KW - Fertility KW - physiology KW - Glutathione Peroxidase KW - deficiency KW - Glutathione KW - Infertility, Male KW - Oxidation-Reduction KW - Oxidative Stress KW - Selenocysteine KW - Selenoproteins KW - enzymology N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Selenium in nutrition -- Selenocysteine as the 21st aminoacid -- Eukaryotic selenocysteine-containing proteins -- GPx4 and the Sec-glutathione peroxidases -- The redox chemistry of GPx4 and spermatogenesis -- Selenium and male fertility -- Whole body KO of GPx4 -- Selenoproteins involved in spermatogenesis -- Spermatozoa GPx4 activity as a biomarker of fertility; Access restricted to subscribers UR - https://hstalks.com/bs/388/ UR - https://hstalks.com/bs/p/21/ ER -