TY - ADVS AU - Buyse,Marc E. TI - Biomarkers and surrogate endpoints in randomized clinical trials T2 - Design and analysis of randomized clinical trials : design, analysis & theory, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Antineoplastic agents KW - Testing KW - Biochemical markers KW - Clinical trials KW - Statistical methods KW - Research KW - Design KW - Tumor markers KW - Antineoplastic Agents KW - therapeutic use KW - Biomarkers, Tumor KW - Biometry KW - methods KW - Neoplasms KW - drug therapy KW - Prognosis KW - Randomized Controlled Trials as Topic KW - statistics & numerical data KW - Research Design N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Definitions (prognostic biomarker, predictive biomarker, surrogate endpoint) -- Statistical validation of biomarkers -- Examples of surrogate endpoints in oncology; Access restricted to subscribers UR - https://hstalks.com/bs/554/ UR - https://hstalks.com/bs/p/15/ ER -