TY - ADVS AU - Campbell,Matthew TI - Protective inflammasome activation in AMD T2 - Macular degeneration, PY - 2016/// CY - London PB - Henry Stewart Talks KW - Choroid KW - Diseases KW - Eye KW - Blood vessels KW - Inflammation KW - Neovascularization KW - Retina KW - Retinal degeneration KW - Age factors KW - Age Factors KW - Carrier Proteins KW - physiology KW - Choroidal Neovascularization KW - etiology KW - prevention & control KW - Inflammasomes KW - Interleukin-18 KW - Macular Degeneration KW - immunology KW - pathology KW - Optic Disk Drusen KW - metabolism KW - Retinal Pigment Epithelium KW - Vascular Endothelial Growth Factors N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Prevalence & forms of AMD -- The NLRP3 inflammasome in AMD -- Laser-induced CNV -- IL-18 anti-angiogenic properties -- IL-18 regulation of vascular permeability in choroid -- IL-18 in human & primate retinal pigment epithelium (RPE) -- IL-18 regulation of VEGF activity, secretion & expression levels -- IL-18 regulation of CNV development -- IL-18 utility as an additive therapy for wet AMD; Access restricted to subscribers UR - https://hstalks.com/bs/3380/ UR - https://hstalks.com/bs/p/979/ ER -