TY  - ADVS
AU  - Duchen,Michael R.
TI  - Mitochondria and calcium signaling in cell life and cell death
T2  - Mitochondria in health and disease,
PY  - 2018///
CY  - London
PB  - Henry Stewart Talks
KW  - Calcium
KW  - Metabolism
KW  - Physiological effect
KW  - Cell death
KW  - Cellular signal transduction
KW  - Mitochondria
KW  - Calcium Metabolism Disorders
KW  - Calcium Signaling
KW  - Cell Death
KW  - Cytosol
KW  - metabolism
KW  - physiology
KW  - Mitochondrial Membrane Transport Proteins
KW  - mitochondrial permeability transition pore
KW  - Neuromuscular Diseases
KW  - Oxidative Phosphorylation
KW  - Permeability
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Calcium signalling, ubiquitous and associated with increased energy demand -- Mitochondria machinery to for taking up calcium from the cytosol -- The transfer of calcium from cytosol to mitochondria (stimulation of oxidative phosphorylation & matching energy supply with demand) -- Mutations in proteins that regulate mitochondrial calcium uptake (causation of a neuromuscular disease, possibly by mitochondrial calcium overload) -- Acute severe calcium overload causes cell death during reperfusion of ischaemic tissues -- The permeability transition pore, a potential therapeutic target; Access restricted to subscribers
UR  - https://hstalks.com/bs/3684/
UR  - https://hstalks.com/bs/p/1034/
ER  -