TY - ADVS AU - Vries,Elga de TI - The blood-brain barrier in multiple sclerosis: a target for treatment? T2 - The blood-brain barrier : understanding the regulatory gatekeeper between brain and body, PY - 2018/// CY - London PB - Henry Stewart Talks KW - Blood-brain barrier KW - Multiple sclerosis KW - Blood-Brain Barrier KW - physiology KW - Brain KW - physiopathology KW - Central Nervous System Diseases KW - Endothelial Cells KW - Multiple Sclerosis KW - drug therapy KW - pathology N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2008 under the title: The blood-brain barrier in multiple sclerosis lesion; Contents: Brain endothelium and the neurovascular unit -- Multiple sclerosis (MS) disease course and pathology -- Blood brain barrier (BBB) breakdown -- Mechanisms of BBB failure in MS -- Gliosis and neurodegeneration -- Irreversible tissue damage through infiltration of immune cells -- Targets for MS drugs -- Treatments and their impact on BBB dysfunction -- Restoring CNS homeostasis; Access restricted to subscribers UR - https://hstalks.com/bs/773/ UR - https://hstalks.com/bs/p/277/ ER -