TY  - ADVS
AU  - Hell,Johannes
TI  - β2 adrenergic receptor complexes mediate localized cAMP signaling
T2  - Ion channels : mediators of ion currents across cell membranes,
PY  - 2018///
CY  - London
PB  - Henry Stewart Talks
KW  - Beta adrenoceptors
KW  - Calcium channels
KW  - Cardiovascular system
KW  - Physiology
KW  - Cellular signal transduction
KW  - Central nervous system
KW  - Molecular aspects
KW  - alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
KW  - Calcium Channels, L-Type
KW  - physiology
KW  - Cyclic AMP
KW  - Neuronal Plasticity
KW  - Neurons
KW  - Receptors, Adrenergic, beta-2
KW  - metabolism
KW  - Receptors, AMPA
KW  - Receptors, Glutamate
KW  - Signal Transduction
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2011 under the title:  Beta-adrenergic receptor - ion channel signaling complexes; Contents: Introduction to signaling by beta adrenergic receptors and the corresponding regulation of the L-type calcium channel Cav1.2 in brain and heart -- Cav1.2 signaling complex in brain -- Role of the beta2 adrenergic receptor, Cav1.2, and their association in beta adrenergic signaling in the brain and in synaptic plasticity -- Introduction to the signaling complex formed by the beta2 adrenergic receptor with the AMPA-type glutamate receptor (AMPAR) -- AMPAR signaling complex in brain -- Conclusion: formation of a functional unit between the AMPAR and Cav1.2 whose activity is driven by beta2 adrenergic stimulation to augment synaptic strength in a lasting manner; Access restricted to subscribers
UR  - https://hstalks.com/bs/1956/
UR  - https://hstalks.com/bs/p/533/
ER  -