TY - ADVS AU - Tumey,L.Nathan TI - Current challenges in the design of antibody-drug conjugates T2 - Periodic reports : advances in clinical interventions and research platforms, PY - 2018/// CY - London PB - Henry Stewart Talks KW - Clinical trials KW - Drug development KW - Drugs KW - Design KW - Immunotherapy KW - Pharmaceutical chemistry KW - Antibodies KW - administration & dosage KW - pharmacology KW - therapeutic use KW - Antineoplastic Agents KW - immunology KW - toxicity KW - Clinical Trials as Topic KW - Drug Design KW - Immunoconjugates KW - pharmacokinetics KW - Neoplasms KW - drug therapy N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: How antibody-drug conjugates work -- How payloads are selected -- Methods for minimizing toxicity and improving potency -- Examples of drugs in clinical trials/market; Access restricted to subscribers UR - https://hstalks.com/bs/3814/ UR - https://hstalks.com/bs/p/1048/ ER -