TY - ADVS AU - Scherrmann,Jean-Michel TI - Expression vs. function of ABC transporters at the blood-brain barrier T2 - The blood-brain barrier : understanding the regulatory gatekeeper between brain and body, PY - 2019/// CY - London PB - Henry Stewart Talks KW - Biological transport KW - Blood-brain barrier KW - Drug development KW - Proteins KW - Metabolism KW - ATP Binding Cassette Transporter, Subfamily B, Member 1 KW - ATP Binding Cassette Transporter, Subfamily G, Member 2 KW - ATP-Binding Cassette Transporters KW - Blood-Brain Barrier KW - metabolism KW - Gene Expression KW - Multidrug Resistance-Associated Proteins N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2008; Contents: Introduction to the ABC superfamily and the blood-brain barrier (BBB) -- ABCB and P-glycoprotein (ABCB1) at the BBB -- ABCG and BCRP (ABCG2) at the BBB -- ABCC and the Multi-Drug Resistance Proteins (MRPs) at the BBB -- ABC in isolated human brain microvessels -- Pre-clinical and clinical impact in central nervous system research and drug development; Access restricted to subscribers UR - https://hstalks.com/bs/769/ UR - https://hstalks.com/bs/p/277/ ER -