TY  - ADVS
AU  - Hébert,Terry
TI  - What can we learn from conformational profiling of GPCRs?
T2  - G Protein-Coupled Receptors (GPCRs) signaling in health and disease,
PY  - 2020///
CY  - London
PB  - Henry Stewart Talks
KW  - Cellular signal transduction
KW  - Drug development
KW  - Methodology
KW  - G proteins
KW  - Receptors
KW  - Proteins
KW  - Conformation
KW  - Chemistry, Pharmaceutical
KW  - methods
KW  - trends
KW  - Drug Discovery
KW  - Protein Conformation
KW  - Receptors, G-Protein-Coupled
KW  - chemistry
KW  - metabolism
KW  - Signal Transduction
KW  - drug effects
KW  - physiology
KW  - Technology, Pharmaceutical
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Biased signaling will have an impact in clinical medicine -- Pharma is moving into using signaling signatures to capture information during drug discovery process -- The information of signaling signatures can never be "complete" -- Conformational profiling may offer a huge time savings rather than extending signaling signatures -- Conformational profiling needs to be done in relevant cell, tissue and animal models; Access restricted to subscribers
UR  - https://hstalks.com/bs/4143/
UR  - https://hstalks.com/bs/p/1083/
ER  -