TY  - ADVS
AU  - Pan,Ying-Xian
TI  - Biased signaling at mu opioid receptor splice variants
T2  - G Protein-Coupled Receptors (GPCRs) signaling in health and disease,
PY  - 2020///
CY  - London
PB  - Henry Stewart Talks
KW  - Cellular signal transduction
KW  - G proteins
KW  - Receptors
KW  - Opioids
KW  - Alternative Splicing
KW  - Drug Tolerance
KW  - Morphine
KW  - OPRM1 protein, human
KW  - Receptors, G-Protein-Coupled
KW  - metabolism
KW  - Receptors, Opioid, mu
KW  - genetics
KW  - Signal Transduction
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Extensive alternative pre-mRNA splicing of the mu opioid receptor gene (OPRM1) -- Distinct intracellular C-terminal tails in different full-length 7TM C-terminal variants -- Distinct in vivo functions of several C-terminal tails -- In vivo truncation of C-terminal tails encoded by E7 affects morphine tolerance and reward -- In vivo truncation of C-terminal tails encoded by E4 affects morphine tolerance and dependence; Access restricted to subscribers
UR  - https://hstalks.com/bs/4241/
UR  - https://hstalks.com/bs/p/1083/
ER  -