TY - ADVS AU - Brown,David A. TI - M-current and its role in neuronal physiology T2 - Ion channels : mediators of ion currents across cell membranes, PY - 2020/// CY - London PB - Henry Stewart Talks KW - Ion channels KW - Neurons KW - Physiology KW - Action Potentials KW - Axon Initial Segment KW - Cholinergic Agents KW - Interneurons KW - Membrane Potentials KW - Neural Conduction KW - physiology KW - Ranvier's Nodes N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2011; Contents: Basic properties -- Molecular composition -- Inhibition by acetycholine and mechanism of inhibition -- Functions: membrane potential clamp -- Control of action potential discharges -- Control of nociceptive sensory excitation -- Suppression of repetitive discharges at nodes of Ranvier -- Regulation of action potential threshold at axon initial segment -- Suppression of epileptiform discharges in central neurons -- Contribution of M-channel inhibition to cholinergic excitation; Access restricted to subscribers UR - https://hstalks.com/bs/1952/ UR - https://hstalks.com/bs/p/533/ ER -