TY  - SOUND
AU  - Gibson,Toby
TI  - The role of short linear motifs (SLiMs) in SARS-CoV-2 entry into human cells
T2  - Interviews on Covid-19,
PY  - 2021///
CY  - London
PB  - Henry Stewart Talks
KW  - Cell receptors
KW  - Coronaviruses
KW  - COVID-19 (Disease)
KW  - Research
KW  - Treatment
KW  - Drug development
KW  - Host-virus relationships
KW  - Viruses
KW  - Receptors
KW  - Amino Acid Motifs
KW  - Angiotensin-Converting Enzyme 2
KW  - chemistry
KW  - physiology
KW  - Antiviral Agents
KW  - Chloroquine
KW  - Chlorpromazine
KW  - COVID-19
KW  - therapy
KW  - virology
KW  - Endocytosis
KW  - Host Microbial Interactions
KW  - Integrins
KW  - Models, Biological
KW  - Molecular Targeted Therapy
KW  - SARS-CoV-2
KW  - pathogenicity
KW  - Spike Glycoprotein, Coronavirus
KW  - Virus Internalization
N1  - Audio interview; Title from title frames; Contents: Rationale and approach to investigating ACE2 and integrin SLiMs -- Update on the mechanism of ACE2- and integrin-mediated viral entry into cells -- SLiMs and their essential role in cellular endocytosis -- Possibility of targeting specific SLiMs as a novel antiviral therapy -- Efficacy of Chloroquine and Chlorpromazine as potential small-molecule therapeutics against viral entry into cells -- The power of interfering with integrin-dependent cellular endocytosis as a proactive defense against coronaviruses; Access restricted to subscribers
UR  - https://hstalks.com/bs/4608/
UR  - https://hstalks.com/bs/p/1060/
ER  -