TY  - ADVS
AU  - Debyser,Zeger
TI  - Cellular cofactors of HIV integrase: from target identification to discovery of LEDGINs 
T2  - Antivirals : latest developments and future progress,
PY  - 2021///
CY  - London
PB  - Henry Stewart Talks
KW  - Antiviral agents
KW  - Drug Development
KW  - HIV (Viruses)
KW  - Enzymes
KW  - Inhibitors
KW  - HIV infections
KW  - Treatment
KW  - Antiviral Agents
KW  - pharmacology
KW  - Drug Discovery
KW  - HIV Infections
KW  - drug therapy
KW  - HIV Integrase
KW  - metabolism
KW  - HIV
KW  - drug effects
KW  - Intercellular Signaling Peptides and Proteins
KW  - lens epithelium-derived growth factor
KW  - transportin SR2
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2011; Contents: Cellular cofactors of HIV as novel antiviral targets -- LEDGF/p75 is a tethering factor of HIV integrase -- Identification of LEDGF/p75 as binding partner of integrase -- Characterization of the interaction -- Validation of integrase -- LEDGF/p75 interaction as antiviral target -- Assay and Drug Development -- Transportin -- SR2 is a nuclear import factor; Access restricted to subscribers
UR  - https://hstalks.com/bs/2077/
UR  - https://hstalks.com/bs/p/613/
ER  -