TY - ADVS AU - Singh,Ritu TI - Laboratory methods for the in vitro study of drug metabolism T2 - The biomedical & life sciences collection, PY - 2021/// CY - London PB - Henry Stewart Talks KW - Drug development KW - Drugs KW - Metabolism KW - Enzymes KW - Drug Discovery KW - methods KW - Enzyme Induction KW - Enzyme Inhibitors KW - pharmacology KW - In Vitro Techniques KW - Inactivation, Metabolic KW - Kinetics KW - Metabolic Clearance Rate KW - Models, Biological KW - Pharmaceutical Preparations KW - metabolism N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Major classes of drug-metabolizing enzymes -- Co-factor requirement for in vitro incubations -- Practical aspects of conducting in vitro assays -- In vitro assays conducted during drug discovery and development -- Clearance estimation -- Kinetic parameter determination -- Enzyme inhibition -- Enzyme induction -- Enzyme reaction phenotyping; Access restricted to subscribers UR - https://hstalks.com/bs/4652/ ER -