TY - ADVS AU - Gillespie,S.H. TI - Application of whole genome sequencing in tuberculosis clinical trials T2 - The biomedical & life sciences collection, PY - 2021/// CY - London PB - Henry Stewart Talks KW - Antitubercular agents KW - Clinical trials KW - Methodology KW - Gene mapping KW - Tuberculosis KW - Chemotherapy KW - Genetic aspects KW - Antitubercular Agents KW - therapeutic use KW - Clinical Trials as Topic KW - methods KW - Coinfection KW - Genomics KW - Mycobacterium tuberculosis KW - genetics KW - Recurrence KW - Reinfection KW - drug therapy KW - microbiology KW - Whole Genome Sequencing N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Introduction to tuberculosis clinical trials and M. tuberculosis typing -- Understanding mixed infections and their impact on clinical trials -- How to distinguish relapse from reinfection and to determine emergent resistant strains -- How to establish such methods in the context of trials -- outlining the challenges that are still to be overcome; Access restricted to subscribers UR - https://hstalks.com/bs/4659/ ER -