TY - ADVS AU - Cappello,Francesco AU - Macario,Alberto J.L. TI - Mitochondrial chaperonin Hsp60: locations, functions and pathology T2 - Protein homeostasis : folding proteins and maintaining the protein-protein interaction networks, PY - 2021/// CY - London PB - Henry Stewart Talks KW - Cancer KW - Etiology KW - Diseases KW - Causes and theories of causation KW - Molecular chaperones KW - Chaperonin 60 KW - Molecular Chaperones KW - adverse effects KW - physiology KW - Neoplasms KW - etiology KW - metabolism N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2012; Contents: Chaperonology: the study of molecular chaperones in all their aspects, normal and pathological -- The chaperoning system: the entire complement of chaperones in an organism, including co-chaperones and co-factors -- Chaperonopathies: diseases in which abnormal chaperones play a pathogenic role -- Hsp60: the mitochondrial chaperonin Cpn60 -- Genetic Hsp60 chaperonopathies: pathologic conditions in which Hsp60 mutations are involved as etiologic-pathogenic factors -- Hsp60 in cancer: Hsp60 chaperonopathies by mistake, in which the chaperonin helps the tumour rather than the patient; Access restricted to subscribers UR - https://hstalks.com/bs/2231/ UR - https://hstalks.com/bs/p/641/ ER -