TY  - ADVS
AU  - Michalak,Marek
TI  - The endoplasmic reticulum: protein folding and control of calcium homeostasis 
T2  - The endoplasmic reticulum : fundamentals and role in disease,
PY  - 2022///
CY  - London
PB  - Henry Stewart Talks
KW  - Calcium in the body
KW  - Calcium
KW  - Physiological effect
KW  - Endoplasmic reticulum
KW  - Protein folding
KW  - Alzheimer Disease
KW  - Calcium Channels
KW  - Calcium Signaling
KW  - metabolism
KW  - Calreticulin
KW  - Charcot-Marie-Tooth Disease
KW  - Cystic Fibrosis
KW  - Endoplasmic Reticulum
KW  - Fibrosis
KW  - Homeostasis
KW  - physiology
KW  - Protein Folding
KW  - Stress, Physiological
KW  - Unfolded Protein Response
KW  - ursodoxicoltaurine
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Quality control -- Chaperones and folding enzymes in the ER -- Prevention of the deployment of misfolded proteins -- Impaired protein folding in Alzheimer's disease, CMT and cystic fibrosis -- Deficiency in ER calcium-binding chaperones impacts embryonic development; Contents:Update talk: ER stress -- The Unfolded Protein Response (UPR) -- ER stress sensors --  Inositol-Requiring Element 1 (IRE1 alpha) -- Stress-induced activation of the calreticulin gene -- Targeting IRE1 alpha to prevent cardiac fibrosis  -- TUDCA prevents cardiac fibrosis; Access restricted to subscribers
UR  - https://hstalks.com/bs/92/
UR  - https://hstalks.com/bs/p/17/
ER  -