TY - ADVS AU - Shaw,Pamela J. TI - SOD1-related ALS: what has it told us about motor neuron degeneration? Part 2 of 2 T2 - ALS and other motor neuron disorders, PY - 2022/// CY - London PB - Henry Stewart Talks KW - Amyotrophic lateral sclerosis KW - Motor neurons KW - Diseases KW - Gene therapy KW - Treatment KW - Nervous system KW - Degeneration KW - Amyotrophic Lateral Sclerosis KW - genetics KW - pathology KW - therapy KW - Brain KW - Disease Progression KW - Genetic Therapy KW - Glutamates KW - Models, Genetic KW - Motor Neuron Disease KW - Motor Neurons KW - Mutation KW - Nerve Degeneration KW - Superoxide Dismutase KW - Superoxide Dismutase-1 N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Mechanisms of motor neuron injury in the presence of SOD1 mutations -- glutamate-mediated excitotoxicity -- Determinants of fast and slow disease progression -- Therapeutic approaches including gene therapy; Access restricted to subscribers UR - https://hstalks.com/bs/4955/ UR - https://hstalks.com/bs/p/977/ ER -