TY - ADVS AU - Hruby,Victor J. TI - Chemical synthesis of peptides and peptide libraries T2 - Chemical biology : the role of chemistry in our fundamental understanding of biology , PY - 2022/// CY - London PB - Henry Stewart Talks KW - Amino acid sequence KW - Peptides KW - Drug Design KW - Peptide Library KW - chemistry N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2008; Contents: Peptide and protein synthesis is the most robust of all synthetic chemistries -- Very large combinatorial libraries with billions of different peptides are possible -- Highly constrained peptides with specific secondary (phi/psi space) and tertiary (chi space) structures can be designed and synthesized -- Peptides stable to proteolytic degradation and able to cross BBB can be synthesized -- Peptides designed and synthesized with potent and selective bioactivities -- Many excellent drugs -- Peptide synthesis a critical tool for all aspects of chemical biology; Access restricted to subscribers UR - https://hstalks.com/bs/943/ UR - https://hstalks.com/bs/p/279/ ER -