TY  - ADVS
AU  - Evans,William E.
TI  - Genetic polymorphism of thiopurine methyltransferase and thiopurine therapy: from molecular genetics to clinical medicine 
T2  - Cancer therapy : latest thinking in efficacy and toxicity ,
PY  - 2022///
CY  - London
PB  - Henry Stewart Talks
KW  - Cancer
KW  - Chemotherapy
KW  - Methyltransferases
KW  - Molecular genetics
KW  - Pharmacogenomics
KW  - Azathioprine
KW  - Gene Frequency
KW  - Mercaptopurine
KW  - genetics
KW  - metabolism
KW  - Molecular Biology
KW  - Neoplasms
KW  - complications
KW  - drug therapy
KW  - Pharmacogenetics
KW  - Pharmacogenomic Testing
KW  - Polymorphism, Genetic
KW  - thiopurine methyltransferase
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2009; Contents: Pharmacogenomics to optimize cancer chemotherapeutics -- The genetic polymorphism of thiopurine methyltransferase (TPMT) -- Its influence on thiopurine (e.g., mercaptopurine, azathioprine) therapy -- Molecular and biochemical basis of this pharmacogenetic trait -- Clinical diagnostic widely used to individualize and optimize thiopurine therapy for cancer and other diseases -- Update talk: Hematologic toxicity of thiopurines -- Update talk: TPMT -- Update talk: NUDT15 -- Update talk: Ancestry-related differences in allele frequency; Access restricted to subscribers
UR  - https://hstalks.com/bs/1121/
UR  - https://hstalks.com/bs/p/385/
ER  -