TY  - BOOK
AU  - Eswari,J.Satya
AU  - Dhagat,Swasti
AU  - Yadav,Manisha
TI  - Computer-Aided Design of Antimicrobial Lipopeptides As Prospective Drug Candidates
SN  - 9781351018296
AV  - RS431.P37 
U1  - 615.10285 23
PY  - 2019///
CY  - Boca Raton
PB  - CRC Press LLC
KW  - MEDICAL / Pharmacy
KW  - bisacsh
KW  - SCIENCE / Chemistry / General
KW  - SCIENCE / Chemistry / Physical & Theoretical
KW  - Peptide antibiotics
KW  - Design
KW  - Drugs
KW  - Computer-aided design
KW  - Drug development
N1  - Description based upon print version of record
N2  - Increase in antibiotic resistance has forced researchers to develop new drugs against microorganisms. Lipopeptides are produced as secondary metabolites by some microorganisms. Computer-aided Design of Antimicrobial Lipopeptides as Prospective Drug Candidates provides the identification of novel ligands for different antimicrobial lipopeptides. Along with identification, it also provides some of the in silico drug design processes, namely homology modelling, molecular docking, QSAR studies, drug ADMET studies and pharmacophore studies to check the ligand-lipopeptide interaction. Some lipopeptides have shown anti-cancerous properties too, and this book discusses the required templates to design new drugs using computational techniques. Key Features: Focuses on the use lipopeptides as new antimicrobial compounds Presents the basics of in silico modelling for design and development of new drug molecules, and is therefore of interest to beginners in the field Provides a step-by-step process for identification of drug molecules and testing its efficacy in silico Couples with courses on patents and intellectual property rights
UR  - https://www.taylorfrancis.com/books/9781351018302
UR  - http://www.oclc.org/content/dam/oclc/forms/terms/vbrl-201703.pdf
ER  -