TY  - ADVS
AU  - Gagneux,Sébastian
TI  - Fitness and compensation
T2  - Antibiotic resistance : from genes to global prevalence,
PY  - 2009///
CY  - London
PB  - Henry Stewart Talks
KW  - Drug Resistance, Microbial
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Concept of Darwinian fitness -- Understanding the fitness impact of drug resistance -- Mathematical models -- Reversal of drug resistance in bacteria -- How to measure fitness -- The molecular epidemiology approach -- Effect of drug resistance mutations -- Environment effects on fitness measurements -- Effect of strain genetic background -- Pre-adapted strain "families" -- Biogeography of M. tuberculosis -- Compensatory evolution -- Experimental evidence -- Compensation prevents reversion to drug sensitivity -- Types of compensatory mutations -- Questions for future research -- Comparative genomics; Access restricted to subscribers
UR  - https://hstalks.com/bs/1533/
UR  - https://hstalks.com/bs/p/442/
ER  -