TY - ADVS AU - Coates,Anthony R.M. TI - Overcoming resistance through novel drug targets T2 - Antibiotic resistance : from genes to global prevalence, PY - 2009/// CY - London PB - Henry Stewart Talks KW - Drug Resistance, Microbial N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Urgent need for new antibiotics -- Why are so few antibiotics reaching the market -- Pharmaceutical companies leaving the research arena -- Targets -- Bacterial molecules (genomics) -- Problems with the genomic approach -- Bacteriophage -- Treatments and problems with bacteriophages -- Whole bacteria -- Conventional multiplying bacteria -- Non-culturable bacteria -- Non-multiplying bacteria -- Tuberculosis, bacterial endocarditis, catheter infections and prosthesis infections -- Ways of making new antibiotics against whole live bacteria -- Potential advantages and problems of making new antibiotics which kill non-multiplying and multiplying bacteria -- Standardization; Access restricted to subscribers UR - https://hstalks.com/bs/1548/ UR - https://hstalks.com/bs/p/442/ ER -