TY - ADVS AU - Hoffmann,J. TI - The anti-microbial defense of Drosophila: a paradigm for innate immunity T2 - Innate immunity : host recognition and response in health and disease, PY - 2009/// CY - London PB - Henry Stewart Talks KW - Drosophila KW - Immunity, Innate N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The insect host defense is a multifaceted process -- Systemic anti-microbial response in Drosophila -- NF-kB: a central transactivator in immune responses -- Gene cascade -- The Toll pathway -- Imd pathway mutants are sensitive to bacterial infections -- Toll pathway mutants are sensitive to fungal infections -- TLR family members and their ligands -- The semmelweis (seml) mutation compromises the anti-gram-positive defense -- Structural aspects of PGRPs -- NF-kB activation by Toll and IMD in Drosophila -- Investigating the response of Drosophila to virus infection -- Response to RNA virus infections -- Keeping parasite numbers low: role of the mosquito immune system -- Losses and amplification of Plasmodium in A. gambiae -- Cactus -- ThioEster-containing Protein 1 (TEP1); Access restricted to subscribers UR - https://hstalks.com/bs/1279/ UR - https://hstalks.com/bs/p/437/ ER -