TY - ADVS AU - Bonini,Nancy M. TI - Human neurodegenerative disease: insights from Drosophila genetics T2 - The legacy of Drosophila genetics : from 'defining the gene' to 'analyzing genome function', PY - 2008/// CY - London PB - Henry Stewart Talks KW - Drosophila KW - genetics KW - Neurodegenerative Diseases N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The fly as a model for human disease -- Modelling human polyglutamine disease -- Molecular chaperones as modifiers of polyglutamine disease using the fly -- Importance and impact of disease protein function for effects of the toxic mutant protein -- Insights from the fly on the mutational basis of disease, in instability of the trinucleotide repeat expansion; Access restricted to subscribers UR - https://hstalks.com/bs/988/ UR - https://hstalks.com/bs/p/283/ ER -