TY  - ADVS
AU  - Humphries,Steve E.
TI  - Familial hyperchlolesterolaemia: a monogenic cause of early CHD 
T2  - Genetics of cardiovascular disease : genetic interactions in a multifactorial disease,
PY  - 2008///
CY  - London
PB  - Henry Stewart Talks
KW  - Cardiovascular Diseases
KW  - genetics
KW  - Hypercholesterolemia
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Clinical diagnostic criteria -- Prevalence in UK -- Effects of statins on cholesterol and CHD risk lowering -- The 3 genes where mutations cause FH (LDLR, APOB, PCSK9) -- Clinical Genetics Diagnostic service for FH and examples in families -- Cascade testing for FH patients using LDL cholesterol levels -- The Overlap problem -- The Simon Broome FH register project and the high risk of early CHD in those with an LDLR and PCSK9 mutation -- The LDLR mutation database -- Ethical issues about genetic testing for FH -- Clinical questions in the management of FH -- FH testing and insurance; Access restricted to subscribers
UR  - https://hstalks.com/bs/1059/
UR  - https://hstalks.com/bs/p/379/
ER  -