TY  - ADVS
AU  - Bird,A.P.
TI  - DNA methylation
T2  - Epigenetics : concepts, theories, paradigms and mechanisms,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Epigenesis, Genetic
KW  - Eukaryotic Cells
KW  - Gene Expression Regulation
KW  - Transcription, Genetic
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system; Access restricted to subscribers
UR  - https://hstalks.com/bs/114/
UR  - https://hstalks.com/bs/p/18/
ER  -