TY  - ADVS
AU  - Hardy,John
TI  - Similarities between prion diseases and other neurodegenerative diseases
T2  - Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi,
PY  - 2008///
CY  - London
PB  - Henry Stewart Talks
KW  - Amyloid
KW  - Prions
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Pathology of diseases -- Prion diseases -- The first family with a prion mutation: Creutzfeldt-Jacob disease -- Alzheimer's disease -- 7Mb duplication of locus around APP -- APP probably a locus for "sporadic" Alzheimer's disease -- Diseases with only Lewy bodies: Parkinson's disease and Lewy body dementia -- Iowa kindred structure -- alpha-synuclein -- Diseases with only Tau pathology -- The microtubule associated protein tau -- Evolution of human tau haplotypes -- Tagging SNPs selection -- More complex than just H1/H2 -- Association with PSP is driven by H1c allele -- Primary tauopathies -- "Prion-like " behaviour of A-beta -- Does the "spreading" of diseases reflect a less extreme version of infection? -- Alzheimer's disease is a neuroanatomical disease which "spreads" -- Parkinson's disease pathology also seems to spread -- MAPT and alpha-synuclein in the extracellular compartment?; Access restricted to subscribers
UR  - https://hstalks.com/bs/956/
UR  - https://hstalks.com/bs/p/282/
ER  -