TY - ADVS AU - Savinov,Sergey N. TI - SICLOPPS: genetic system for production of backbone cyclized peptides T2 - Chemical biology : the role of chemistry in our fundamental understanding of biology, PY - 2008/// CY - London PB - Henry Stewart Talks KW - Biology KW - Chemistry N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: SICLOPPS: method for production of genetically encoded backbone cyclized peptides -- Cyclic peptides as probes of biological function -- Splicing of a circularly rearranged split-intein -- Production and isolation of backbone cyclic peptides -- Generation of combinatorial libraries -- Selection of protein-protein inhibitors using a bacterial two-hybrid assay -- Biochemical characterization of dissociative inhibitors; Access restricted to subscribers UR - https://hstalks.com/bs/946/ UR - https://hstalks.com/bs/p/279/ ER -