TY - ADVS AU - Goldstein,D.B. TI - Haplotype-based mapping in pharmacogenetics T2 - Genetic epidemiology I : fundamentals, theory, practice and latest developments, PY - 2004/// CY - London PB - Henry Stewart Talks KW - Genetic Predisposition to Disease KW - epidemiology N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Pharmacogenetics: a simpler complex trait? -- Mapping strategies: map-based and sequence-based -- Tagging SNPs: definition and assessment -- Case study: tagging in 56 drug transport and metabolism genes -- tSNP efficiency: influence of sample size, SNP frequency and SNP density -- Case study: ABCB1 and anti-epileptic drug resistance -- Associated interval; Access restricted to subscribers UR - https://hstalks.com/bs/39/ UR - https://hstalks.com/bs/p/25/ ER -