TY - ADVS AU - Frank,J. TI - Structural insights into aminoacyl-tRNA delivery by EF-Tu and translocation by EF-G T2 - The mechanisms of ribosome function : insights into protein synthesis, PY - 2008/// CY - London PB - Henry Stewart Talks KW - Protein Biosynthesis KW - Ribosomal Proteins KW - Ribosomes N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Schematic of elongation cycle -- Role of elongation factors EF-G and EF-Tu -- Molecular mimicry of elongation factors -- Binding positions of factors and tRNA during elongation cycle -- Process of tRNA selection -- Proofreading -- Role of bases A1492 and A1493 -- GTP hydrolysis on EF-Tu -- tRNA as a molecular spring -- Translocation -- Intersubunit ratchet motion -- Induced fit -- FRET studies of ratchet motion -- Hybrid states of tRNA -- Role of GTP hydrolysis in translocation; Access restricted to subscribers UR - https://hstalks.com/bs/806/ UR - https://hstalks.com/bs/p/285/ ER -