TY - ADVS AU - Davies,Kelvin J.A. TI - Introduction to free radicals and the oxygen paradox: oxidative stress in biology, aging & disease T2 - Free radicals and the oxygen paradox : oxidative stress in biology, aging and disease, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Free Radicals KW - Oxidative Stress N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The oxygen paradox -- Oxygen origin -- Free radicals, oxidants and oxidative stress -- Sources of free radicals -- Environmental toxins -- Metabolic sources of free radicals: mitochondrial electron transport, phagocytes, peroxisomes, autooxidation -- Medical and dental sources of free radicals: x-rays, g-rays, drugs -- DNA damage and oxygen radical toxicity -- Antioxidant compounds and enzymes -- The dismutation of superoxide -- Mechanisms of antioxidant enzymes -- Antioxidant defense and repair systems -- Removal of oxidized DNA bases and DNA repair -- Lipolysis and the repair of oxidized lipids and lipid membranes -- Selective proteolytic degradation of oxidized proteins -- The LON protease -- Adaptation to oxidative stress -- Long-term effects of free radicals and oxidative stress: aging and disease; Access restricted to subscribers UR - https://hstalks.com/bs/374/ UR - https://hstalks.com/bs/p/21/ ER -