TY - ADVS AU - Steitz,Thomas A. TI - The structural basis for how the large ribosomal subunit catalyses peptide bond formation T2 - The mechanisms of ribosome function : insights into protein synthesis, PY - 2008/// CY - London PB - Henry Stewart Talks KW - Protein Biosynthesis KW - Ribosomal Proteins KW - Ribosomes N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Overview of protein synthesis by the ribosome -- Nature of the polypeptide exit tunnel in the large subunit -- The ribosome is a ribozyme -- Substrate induced fit at the peptidyl transferase center -- Proton shuttle mechanism and transition state stabilization -- Substrate interactions at the large subunit E-site -- Movie of the peptidyl transferase reaction; Access restricted to subscribers UR - https://hstalks.com/bs/802/ UR - https://hstalks.com/bs/p/285/ ER -