TY  - ADVS
AU  - Allsop,David
TI  - Protein aggregation, metals and oxidative stress in neurodegenerative diseases
T2  - Protein folding, aggregation and design : concepts, experiments, theories and mechanisms,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Neurodegenerative Diseases
KW  - Protein Conformation
KW  - Protein Folding
KW  - Proteins
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Introduction to protein conformational brain diseases -- Alzheimer's disease, A-beta and tau -- A-beta oligomers and toxicity -- A-beta generates hydrogen peroxide -- Results from experiments using electron spin resonance spectroscopy -- Parkinson's disease -- Generation of hydrogen peroxide from alpha synuclein, toxic fragments of the prion protein and the familial British dementia peptide -- Early oligomers appear to generate hydrogen peroxide -- Huntington's disease -- Protein aggregates could be protective -- Potential common toxic pathway for these brain diseases; Access restricted to subscribers
UR  - https://hstalks.com/bs/441/
UR  - https://hstalks.com/bs/p/34/
ER  -