TY - ADVS AU - Whisstock,James TI - Serpins and the serpinopathies T2 - Protein epidemiology : understanding human diseases at the level of protein structure and function, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Peptide Hydrolases KW - Protein Conformation KW - Proteins KW - Serpins KW - deficiency N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Serpins -- Proteases -- Serpin function -- Serpin structure -- Serpin protease interactions -- Role of co-factors in serpin function -- Serpin polymerization and dysfunction -- Antitrypsin deficiency -- Z-antitrypsin -- Mechanism of serpin polymerization -- Other serpin deficiencies -- Antithrombin deficiency -- Neuroserpin polymerization -- Antichymotrypsin deficiency -- Approaches to combat serpinopathies; Access restricted to subscribers UR - https://hstalks.com/bs/73/ UR - https://hstalks.com/bs/p/33/ ER -