TY - ADVS AU - Kolesnick,Richard TI - Endothelial cell apoptosis T2 - Apoptosis : fundamentals, pathways, clinical applications and role in disease, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Apoptosis KW - Endothelial Cells KW - Neoplasms KW - radiotherapy N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Endothelial apoptosis -- Role in tumor response to radiation therapy -- Tissue damage results from depletion of stem cells and cells with clonogenic capacity -- Radiation targets the DNA leading to reproductive (mitosis-associated) or apoptotic cell death -- Modifications of DNA damage recognition and repair pathways determine the level of tissue sensitivity to radiation -- Sphingomyelin -- Ceramide -- GI tract and bone marrow: very radiation responsive -- Growth patterns of tumors -- The two-target model for single-dose radiotherapy of experimental tumors -- Engaging the vascular component of tumor response to radiation; Access restricted to subscribers UR - https://hstalks.com/bs/296/ UR - https://hstalks.com/bs/p/12/ ER -