TY - ADVS AU - Steller,Hermann TI - Regulation of apoptosis: lessons from Drosophila and their implications for human health and disease T2 - Apoptosis : fundamentals, pathways, clinical applications and role in disease, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Apoptosis KW - Drosophila N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Many different signals influence apoptosis -- "Gas" and "brake" model of apoptosis -- Reaper, Hid and Grim -- IAPs and cancer -- Use of Drosophila -- Ubiquitination and apoptosis -- diap1 -- In proliferating tissues, damage induced cell death is compensated by extra growth of the neighboring cells -- Evidence for the "active model" of compensatory proliferation -- Regulation of caspase activation -- Cytochrome c is required for effector caspase activation in Drosophila spermatids -- Cyt-c-d and other apoptosome proteins are required for normal developmental apoptosis in the Drosophila retina -- Generation of Sept4-null mice -- Acquired characteristics of cancer cells; Access restricted to subscribers UR - https://hstalks.com/bs/277/ UR - https://hstalks.com/bs/p/12/ ER -