TY - ADVS AU - Breen,Gerome TI - Cocaine and amphetamine addiction genetics T2 - Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Pharmacogenetics KW - Psychopharmacology KW - Psychotropic Drugs N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Heritability of cocaine and other addictions -- Gene-environment interactions and addiction -- The Dopamine transporter gene (SLC6A3) -- Brazilian Cocaine Association sample -- Case-control cohort from Sao Paulo, Brazil -- Association between the variants and cocaine addiction -- Potential study confounders -- Correcting for population stratification -- Reporter-gene assays indicating that the VNTR is a differential response element -- Functional assay of associated genetic variation -- Different expression levels of the alleles -- Allele and genotype association between DAT-intron 8 VNTR and cocaine -- Similar studies on amphetamine and methamphetamine addiction; Access restricted to subscribers UR - https://hstalks.com/bs/274/ UR - https://hstalks.com/bs/p/35/ ER -