TY  - ADVS
AU  - Neel,Benjamin G.
TI  - SH2-containing PTPs (Shps) in RTK signaling and disease
T2  - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Receptor Protein-Tyrosine Kinases
KW  - Signal Transduction
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Introduction to the PTP superfamily -- Shps, history and overview -- Shp stucture: role of SH2 domains, PTP domains, C-tail -- catalytic mechanism -- Regulation by phosphotyrosyl peptides, phosphorylation, reactive oxygen species -- Overview of physiological functions -- Role in RTK signaling: regulation of Ras/Erk pathway; roles in other downstream cascades -- Shps in disease -- Key questions and challenges for the future; Access restricted to subscribers
UR  - https://hstalks.com/bs/459/
UR  - https://hstalks.com/bs/p/38/
ER  -