TY  - ADVS
AU  - Hunter,Tony
TI  - Receptor tyrosine kinases: function, families and evolution 
T2  - Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Hormones
KW  - Receptor Protein-Tyrosine Kinases
KW  - Signal Transduction
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: History of protein phosphorylation -- Protein kinase bioinformatics -- History of tyrosine phosphorylation and functions of tyrosine kinases -- Genomic catalogues of protein kinases (kinomes) -- The human kinome -- The evolution of kinomes -- The human tyrosine kinase subfamily -- Receptor and nonreceptor tyrosine kinases -- Activation of receptor tyrosine kinases by ligand-induced dimerization -- Signal transduction pathways downstream of receptor tyrosine kinases -- Insulin and IOGF-1 receptor signaling via the mTOR pathway -- mTOR-S6 kinase feedback loop leading to downregulation of the IRS1 docking protein and insulin resistance -- History of Eph receptor tyrosine kinases and their ephrin ligands -- Bidirectional signaling via Eph-ephrin interactions on neighboring cells -- Simultaneous signaling by EphAs and ephrin As in motor neurons -- Compartmentalized signaling by receptor tyrosine kinases and their ligands through localization to discrete membrane domains -- Protein kinases and human disease -- Human cancer genes and protein kinases -- Protein kinases and phosphatases and cancer -- The long road to Gleevec; Access restricted to subscribers
UR  - https://hstalks.com/bs/447/
UR  - https://hstalks.com/bs/p/38/
UR  - https://hstalks.com/bs/p/42/
ER  -