TY  - ADVS
AU  - Morris,Kevin V.
TI  - Small interfering RNA induced transcriptional gene silencing in human cells
T2  - RNA interference : principles and applications,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Cells
KW  - Gene Silencing
KW  - RNA Interference
KW  - RNA, Small Interfering
KW  - Transcription, Genetic
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: How siRNAs mediate transcriptional gene silencing (TGS) in human cells -- Histone methylation -- Dependency on active RNA polymerase II mediated transcription -- siRNA-mediated TGS -- H3K9 and H3K27 methylation of the targeted EF1A promoter -- Nuclear specific delivery of the siRNA -- Antisense strand-specific siRNA-mediated TGS of EF1A -- Targeting of the U3 region of the HIV-1 LTR/promoter -- Antisense strand of siRNA EF2 interacts with FLAG-tagged DNMT3A and the tri-methylated H3K27 methyl mark -- siRNA mediated targeting of genomic regions -- RNA Pol-II function -- Transcriptional gene silencing in human cells; Access restricted to subscribers
UR  - https://hstalks.com/bs/651/
UR  - https://hstalks.com/bs/p/37/
ER  -